One discipline.

Structural biology arrives fragmented — heterogeneous crystal and cryo-EM structures, each in its own protonation and glycosylation state, each re-prepared by hand. EndPoint turns that library into fully parameterised, simulation-ready molecular-dynamics systems through one orchestrated, reproducible pipeline.

Built around TLR7/TLR8 signalling and systemic lupus erythematosus, it produces consistent, solvated, glycosylated, protonation-resolved systems for every structure at once — the basis for the ensemble analysis that surfaces a protein's control points. Configuration is the source of truth, so the same method transfers cleanly to any receptor: no code holds receptor names, PDB IDs or residue numbers.

Dotfiles scatter and drift; every new machine starts from nothing. BoneShell makes the repo authoritative — one idempotent command, and a fresh macOS or Linux machine is identically home: shell, editor, prompt and palette already in sync, with structures built to help it stay that way. Beautiful. Powerful. Prepared.

That one command bootstraps zsh, Oh My Zsh, Starship, pixi, a Nerd Font and a curated toolset — fzf, zoxide, eza, bat, ripgrep — pre-wired and ready. A single visual palette cascades to every consumer (terminal, prompt, editor and beyond), so nothing is hand-synced. Your own aliases and functions live in the tracked repo; secrets stay local and never leave the machine.

The machines you work across thread into a single SSH chain that AI agents can move along — reaching into any system when needed. Configuration stops being disposable and becomes CI-tested infrastructure — your art, and coherence you carry between systems that can adapt with you.

Built to be beautiful, customised to your own flavour, and kept.